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W.SudhaharV.DasA.ChandhriR.Cuervo GrajalH.et al (2018b)

While their mode of action is somewhat different, their clinical effects are overlapping, which include enhancing satiety, delaying gastric emptying, increasing insulin and its sensitivity, decreasing glucagon, and, of course, reducing high glucose levels

It happens to thousands of people every year who have never touched a GLP-1 medication